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Benzimidazole-1,2,3-triazole Hybrid Molecules: Synthesis and Evaluation for Antibacterial/Antifungal Activity

A novel series of hybrid molecules 4a–i and 5a–i were prepared by condensation of 4-(trimethylsilylethynyl)benzaldehyde 1 with substituted o-phenylenediamines. These in turn were reacted with 2-(azidomethoxy)ethyl acetate in a Cu alkyne–azide cycloaddition (CuAAC) to generate the 1,2,3-triazole phar...

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Detalles Bibliográficos
Autores principales: Ouahrouch, Abdelaaziz, Ighachane, Hana, Taourirte, Moha, Engels, Joachim W, Sedra, My Hassan, Lazrek, Hassan B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225497/
https://www.ncbi.nlm.nih.gov/pubmed/25088180
http://dx.doi.org/10.1002/ardp.201400142