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Optimizing Escherichia coli as a protein expression platform to produce Mycobacterium tuberculosis immunogenic proteins

BACKGROUND: A number of valuable candidates as tuberculosis vaccine have been reported, some of which have already entered clinical trials. The new vaccines, especially subunit vaccines, need multiple administrations in order to maintain adequate life-long immune memory: this demands for high produc...

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Detalles Bibliográficos
Autores principales: Piubelli, Luciano, Campa, Manuela, Temporini, Caterina, Binda, Elisa, Mangione, Francesca, Amicosante, Massimo, Terreni, Marco, Marinelli, Flavia, Pollegioni, Loredano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225511/
https://www.ncbi.nlm.nih.gov/pubmed/24252280
http://dx.doi.org/10.1186/1475-2859-12-115