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Cheminformatic models based on machine learning for pyruvate kinase inhibitors of Leishmania mexicana

BACKGROUND: Leishmaniasis is a neglected tropical disease which affects approx. 12 million individuals worldwide and caused by parasite Leishmania. The current drugs used in the treatment of Leishmaniasis are highly toxic and has seen widespread emergence of drug resistant strains which necessitates...

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Detalles Bibliográficos
Autores principales: Jamal, Salma, Scaria, Vinod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225525/
https://www.ncbi.nlm.nih.gov/pubmed/24252103
http://dx.doi.org/10.1186/1471-2105-14-329