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Cheminformatic models based on machine learning for pyruvate kinase inhibitors of Leishmania mexicana
BACKGROUND: Leishmaniasis is a neglected tropical disease which affects approx. 12 million individuals worldwide and caused by parasite Leishmania. The current drugs used in the treatment of Leishmaniasis are highly toxic and has seen widespread emergence of drug resistant strains which necessitates...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225525/ https://www.ncbi.nlm.nih.gov/pubmed/24252103 http://dx.doi.org/10.1186/1471-2105-14-329 |