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Identification of a type I Ca(2+)/Mg(2+)-dependent endonuclease induced in maize cells exposed to camptothecin
BACKGROUND: Camptothecin is a plant alkaloid that specifically binds topoisomerase I, inhibiting its activity and inducing double stranded breaks in DNA and activating the cell responses to DNA damage. RESULTS: Maize cultured cells were incubated in the presence of different concentrations of campto...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225560/ https://www.ncbi.nlm.nih.gov/pubmed/24256432 http://dx.doi.org/10.1186/1471-2229-13-186 |