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Optical tomographic imaging of near infrared imaging agents quantifies disease severity and immunomodulation of experimental autoimmune encephalomyelitis in vivo

BACKGROUND: Experimental autoimmune encephalomyelitis (EAE) is an animal model that captures many of the hallmarks of human multiple sclerosis (MS), including blood–brain barrier (BBB) breakdown, inflammation, demyelination and axonal destruction. The standard clinical score measurement of disease s...

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Detalles Bibliográficos
Autores principales: Eaton, Valerie L, Vasquez, Kristine O, Goings, Gwendolyn E, Hunter, Zoe N, Peterson, Jeffrey D, Miller, Stephen D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225609/
https://www.ncbi.nlm.nih.gov/pubmed/24237884
http://dx.doi.org/10.1186/1742-2094-10-138