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Natural OX40L expressed on human T cell leukemia virus type-I-immortalized T cell lines interferes with infection of activated peripheral blood mononuclear cells by CCR5-utilizing human immunodeficiency virus

BACKGROUND: OX40 ligand (OX40L) co-stimulates and differentiates T cells via ligation of OX40 that is transiently induced on T cells upon activation, resulting in prolonged T cell survival and enhanced cytokine production by T cells. This view has led to the targeting of OX40 as a strategy to boost...

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Detalles Bibliográficos
Autores principales: Kasahara, Daigo, Takara, Azusa, Takahashi, Yoshiaki, Kodama, Akira, Tanaka, Reiko, Ansari, Aftab A, Tanaka, Yuetsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225675/
https://www.ncbi.nlm.nih.gov/pubmed/24238037
http://dx.doi.org/10.1186/1743-422X-10-338