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The Wilms' Tumor Gene WT1 − 17AA/− KTS Splice Variant Increases Tumorigenic Activity Through Up-Regulation of Vascular Endothelial Growth Factor in an In Vivo Ovarian Cancer Model

The Wilms' tumor 1 gene WT1 encodes a zinc transcription factor involved in a variety of cancer-related processes. In this study, we sought to investigate the effects of WT1 splice variants on tumorigenic activity and survival in an in vivo ovarian cancer model. To this end, we established stab...

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Detalles Bibliográficos
Autores principales: Yamanouchi, Keiko, Ohta, Tsuyoshi, Liu, Zhiyang, Oji, Yusuke, Sugiyama, Haruo, Shridhar, Viji, Matsumura, Sohei, Takahashi, Toshifumi, Takahashi, Kazuhiro, Kurachi, Hirohisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225694/
https://www.ncbi.nlm.nih.gov/pubmed/25389453
http://dx.doi.org/10.1016/j.tranon.2014.07.008