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Preparation and Characterization of Novel PBAE/PLGA Polymer Blend Microparticles for DNA Vaccine Delivery

Context. Poly(beta-amino ester) (PBAE) with its pH sensitiveness and Poly(lactic-co-glycolic acid) (PLGA) with huge DNA cargo capacity in combination prove to be highly efficient as DNA delivery system. Objective. To study the effectiveness of novel synthesized PBAE polymer with PLGA blend at differ...

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Detalles Bibliográficos
Autores principales: Balashanmugam, Meenashi Vanathi, Nagarethinam, Sivagurunathan, Jagani, Hitesh, Josyula, Venkata Rao, Alrohaimi, Abdulmohsen, Udupa, Nayanabhirama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225858/
https://www.ncbi.nlm.nih.gov/pubmed/25401137
http://dx.doi.org/10.1155/2014/385135