Proton Release from the Histidine-Tetrad in the M2 Channel of the Influenza A Virus

[Image: see text] The activity of the M2 proton channel of the influenza A virus is controlled by pH. The tautomeric state and conformation of His37, a key residue in the M2 transmembrane four-helix bundle, controls the gating of the channel. Previously, we compared the energetics and dynamics of tw...

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Detalles Bibliográficos
Autores principales: Dong, Hao, Fiorin, Giacomo, DeGrado, William F., Klein, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226308/
https://www.ncbi.nlm.nih.gov/pubmed/25317959
http://dx.doi.org/10.1021/jp5102225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226308/
https://www.ncbi.nlm.nih.gov/pubmed/25317959
http://dx.doi.org/10.1021/jp5102225

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