Interface dynamics explain assembly dependency of influenza neuraminidase catalytic activity

Influenza virus neuraminidase (iNA) is a homotetrameric surface protein of the influenza virus and an established target for antiviral drugs. In contrast to neuraminidases (NAs) of other biological systems (non-iNAs), enzymatic activity of iNA is only observed in a quaternary assembly and iNA needs...

Descripción completa

Detalles Bibliográficos
Autores principales: von Grafenstein, Susanne, Wallnoefer, Hannes G., Kirchmair, Johannes, Fuchs, Julian E., Huber, Roland G., Schmidtke, Michaela, Sauerbrei, Andreas, Rollinger, Judith M., Liedl, Klaus R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226318/
https://www.ncbi.nlm.nih.gov/pubmed/24279589
http://dx.doi.org/10.1080/07391102.2013.855142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226318/
https://www.ncbi.nlm.nih.gov/pubmed/24279589
http://dx.doi.org/10.1080/07391102.2013.855142

Ejemplares similares