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Limited Density of an Antigen Presented by RMA-S Cells Requires B7-1/CD28 Signaling to Enhance T-Cell Immunity at the Effector Phase

The association of B7-1/CD28 between antigen presenting cells (APCs) and T-cells provides a second signal to proliferate and activate T-cell immunity at the induction phase. Many reports indicate that tumor cells transfected with B7-1 induced augmented antitumor immunity at the induction phase by mi...

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Detalles Bibliográficos
Autores principales: Li, Xiao-Lin, Sluijter, Marjolein, Doorduijn, Elien M., Kale, Shubha P., McFerrin, Harris, Liu, Yong-Yu, Li, Yan, Mottamal, Madhusoodanan, Yao, Xin, Du, Fengkun, Gu, Baihan, Hoang, Kim, Nguyen, Yen H., Taylor, Nichelle, Stephens, Chelsea R., van Hall, Thorbald, Zhang, Qian-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226464/
https://www.ncbi.nlm.nih.gov/pubmed/25383875
http://dx.doi.org/10.1371/journal.pone.0108192