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Limited Density of an Antigen Presented by RMA-S Cells Requires B7-1/CD28 Signaling to Enhance T-Cell Immunity at the Effector Phase
The association of B7-1/CD28 between antigen presenting cells (APCs) and T-cells provides a second signal to proliferate and activate T-cell immunity at the induction phase. Many reports indicate that tumor cells transfected with B7-1 induced augmented antitumor immunity at the induction phase by mi...
Autores principales: | Li, Xiao-Lin, Sluijter, Marjolein, Doorduijn, Elien M., Kale, Shubha P., McFerrin, Harris, Liu, Yong-Yu, Li, Yan, Mottamal, Madhusoodanan, Yao, Xin, Du, Fengkun, Gu, Baihan, Hoang, Kim, Nguyen, Yen H., Taylor, Nichelle, Stephens, Chelsea R., van Hall, Thorbald, Zhang, Qian-Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226464/ https://www.ncbi.nlm.nih.gov/pubmed/25383875 http://dx.doi.org/10.1371/journal.pone.0108192 |
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