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Increased Bone Marrow (BM) Plasma Level of Soluble CD30 and Correlations with BM Plasma Level of Interferon (IFN)-γ, CD4/CD8 T-Cell Ratio and Disease Severity in Aplastic Anemia

Idiopathic aplastic anemia (AA) is an immune-mediated bone marrow failure syndrome. Immune abnormalities such as decreased lymphocyte counts, inverted CD4/CD8 T-cell ratio and increased IFN-γ-producing T cells have been found in AA. CD30, a surface protein belonging to the tumor necrosis factor rece...

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Detalles Bibliográficos
Autores principales: Wu, Qingqing, Zhang, Jizhou, Shi, Jun, Ge, Meili, Li, Xingxin, Shao, Yingqi, Yao, Jianfeng, Zheng, Yizhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226501/
https://www.ncbi.nlm.nih.gov/pubmed/25383872
http://dx.doi.org/10.1371/journal.pone.0110787