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Increased Bone Marrow (BM) Plasma Level of Soluble CD30 and Correlations with BM Plasma Level of Interferon (IFN)-γ, CD4/CD8 T-Cell Ratio and Disease Severity in Aplastic Anemia
Idiopathic aplastic anemia (AA) is an immune-mediated bone marrow failure syndrome. Immune abnormalities such as decreased lymphocyte counts, inverted CD4/CD8 T-cell ratio and increased IFN-γ-producing T cells have been found in AA. CD30, a surface protein belonging to the tumor necrosis factor rece...
Autores principales: | Wu, Qingqing, Zhang, Jizhou, Shi, Jun, Ge, Meili, Li, Xingxin, Shao, Yingqi, Yao, Jianfeng, Zheng, Yizhou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226501/ https://www.ncbi.nlm.nih.gov/pubmed/25383872 http://dx.doi.org/10.1371/journal.pone.0110787 |
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