Involvement of TNF-α Converting Enzyme in the Development of Psoriasis-Like Lesions in a Mouse Model

TNF-α plays a crucial role in psoriasis; therefore, TNF inhibition has become a gold standard for the treatment of psoriasis. TNF-α is processed from a membrane-bound form by TNF-α converting enzyme (TACE) to soluble form, which exerts a number of biological activities. EGF receptor (EGFR) ligands,...

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Detalles Bibliográficos
Autores principales: Sato, Kenji, Takaishi, Mikiro, Tokuoka, Shota, Sano, Shigetoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226544/
https://www.ncbi.nlm.nih.gov/pubmed/25384035
http://dx.doi.org/10.1371/journal.pone.0112408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226544/
https://www.ncbi.nlm.nih.gov/pubmed/25384035
http://dx.doi.org/10.1371/journal.pone.0112408

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