High Levels of Soluble Ctla-4 Are Present in Anti-Mitochondrial Antibody Positive, but Not in Antibody Negative Patients with Primary Biliary Cirrhosis

Primary biliary cirrhosis (PBC) is a chronic autoimmune cholestatic liver disease frequently characterized by anti-mitochondrial autoantibodies (AMA). A minority of patients are AMA-negative. Cytotoxic-T-Lymphocyte-Antigen-4 (CTLA-4) is a surface molecule expressed on activated T-cells delivering a...

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Detalles Bibliográficos
Autores principales: Saverino, Daniele, Pesce, Giampaola, Antola, Princey, Porcelli, Brunetta, Brusca, Ignazio, Villalta, Danilo, Tampoia, Marilina, Tozzoli, Renato, Tonutti, Elio, Alessio, Maria Grazia, Bagnasco, Marcello, Bizzaro, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226553/
https://www.ncbi.nlm.nih.gov/pubmed/25383768
http://dx.doi.org/10.1371/journal.pone.0112509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226553/
https://www.ncbi.nlm.nih.gov/pubmed/25383768
http://dx.doi.org/10.1371/journal.pone.0112509

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