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The IGF signalling pathway in Wilms tumours - A report from the ENCCA Renal Tumours Biology-driven drug development workshop

It is hypothesised that Wilms tumour (WT) results from aberrant renal development due to its embryonic morphology, associated undifferentiated precursor lesions (termed nephrogenic rests) and embryonic kidney-like chromatin and gene expression profiles. From the study of overgrowth syndrome-associat...

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Detalles Bibliográficos
Autores principales: Maschietto, Mariana, Charlton, Jocelyn, Perotti, Daniela, Radice, Paolo, Geller, James I, Pritchard-Jones, Kathy, Weeks, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226664/
https://www.ncbi.nlm.nih.gov/pubmed/25478630