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Identification of a DNA methylation signature to predict disease-free survival in locally advanced rectal cancer

In locally advanced rectal cancer a preoperative predictive biomarker is necessary to adjust treatment specifically for those patients expected to suffer relapse. We applied whole genome methylation CpG island array analyses to an initial set of patients (n=11) to identify differentially methylated...

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Detalles Bibliográficos
Autores principales: Gaedcke, Jochen, Leha, Andreas, Claus, Rainer, Weichenhan, Dieter, Jung, Klaus, Kitz, Julia, Grade, Marian, Wolff, Hendrik A., Jo, Peter, Doyen, Jérôme, Gérard, Jean-Pierre, Johnsen, Steven A., Plass, Christoph, Beißbarth, Tim, Ghadimi, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226671/
https://www.ncbi.nlm.nih.gov/pubmed/25261372