A screen for transcription factor targets of Glycogen Synthase Kinase-3 highlights an inverse correlation of NFκB and Androgen Receptor Signaling in Prostate Cancer

Expression of Glycogen Synthase Kinase-3 (GSK-3) is elevated in prostate cancer and its inhibition reduces prostate cancer cell proliferation, in part by reducing androgen receptor (AR) signaling. However, GSK-3 inhibition can also activate signals that promote cell proliferation and survival, which...

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Detalles Bibliográficos
Autores principales: Campa, Victor M., Baltziskueta, Eder, Bengoa-Vergniory, Nora, Gorroño-Etxebarria, Irantzu, Wesołowski, Radosław, Waxman, Jonathan, Kypta, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226675/
https://www.ncbi.nlm.nih.gov/pubmed/25327559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226675/
https://www.ncbi.nlm.nih.gov/pubmed/25327559

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