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Peroxisome proliferator activated receptor alpha inhibits hepatocarcinogenesis through mediating NF-κB signaling pathway

Peroxisome proliferator-activated receptor alpha (PPARα) ligands have been reported to suppress cancer growth. However, the role of PPARα in hepatocarcinogenesis remains unclear. We investigated the functional significance of PPARα in hepatocellular carcinoma (HCC). PPARα-knockout (PPARα(-/-)) mice...

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Detalles Bibliográficos
Autores principales: Zhang, Ning, Chu, Eagle S. H., Zhang, Jingwan, Li, Xiaoxing, Liang, Qiaoyi, Chen, Jie, Chen, Minhu, Teoh, Narci, Farrell, Geoffrey, Sung, Joseph J.Y., Yu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226686/
https://www.ncbi.nlm.nih.gov/pubmed/25327562