Oncogene-triggered suppression of DNA repair leads to DNA instability in cancer

DNA instability is an important contributor to cancer development. Previously, defects in the chromosome segregation and excessive DNA double strand breaks due to the replication or oxidative stresses were implicated in DNA instability in cancer. Here, we demonstrate that DNA instability can directl...

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Detalles Bibliográficos
Autores principales: Yaglom, Julia A., McFarland, Christopher, Mirny, Leonid, Sherman, Michael Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226689/
https://www.ncbi.nlm.nih.gov/pubmed/25252808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226689/
https://www.ncbi.nlm.nih.gov/pubmed/25252808

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