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Oncogene-triggered suppression of DNA repair leads to DNA instability in cancer
DNA instability is an important contributor to cancer development. Previously, defects in the chromosome segregation and excessive DNA double strand breaks due to the replication or oxidative stresses were implicated in DNA instability in cancer. Here, we demonstrate that DNA instability can directl...
Autores principales: | Yaglom, Julia A., McFarland, Christopher, Mirny, Leonid, Sherman, Michael Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226689/ https://www.ncbi.nlm.nih.gov/pubmed/25252808 |
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