TALEN-mediated Nanog disruption results in less invasiveness, more chemosensitivity and reversal of EMT in Hela cells

Emerging evidence suggests that Nanog is involved in cervical tumorigenesis. However, the regulating role of Nanog in tumorigenesis and chemosensitivity are still poorly understood. In this study, Nanog was disrupted by transcription activatorlike effector nucleases (TALEN) in Hela cells and its exp...

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Detalles Bibliográficos
Autores principales: Ding, Yan, Yu, Ai Qing, Li, Cheng Lin, Fang, Juan, Zeng, Yi, Li, Dong Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226691/
https://www.ncbi.nlm.nih.gov/pubmed/25245189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226691/
https://www.ncbi.nlm.nih.gov/pubmed/25245189

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