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Interfering with the interaction between ErbB1, nucleolin and Ras as a potential treatment for glioblastoma

The three oncogenes, ErbB receptors, Ras proteins and nucleolin may contribute to malignant transformation. Previously, we demonstrated that nucleolin could bind both Ras protein and ErbB receptors. We also showed that the crosstalk between the three proteins facilitates anchorage independent growth...

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Detalles Bibliográficos
Autores principales: Goldshmit, Yona, Trangle, Sari Schokoroy, Kloog, Yoel, Pinkas-Kramarski, Ronit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226707/
https://www.ncbi.nlm.nih.gov/pubmed/25261371