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Selective targeting of liver cancer with the endothelial marker CD146

Hepatocellular carcinomas are well-vascularized tumors; the endothelial cells in these tumors have a specific phenotype. Our aim was to develop a new approach for tumor-specific drug delivery with monoclonal antibody targeting of endothelial ligands. CD146, a molecule expressed on the endothelial su...

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Detalles Bibliográficos
Autores principales: Thomann, Stefan, Longerich, Thomas, Bazhin, Alexandr V., Mier, Walter, Schemmer, Peter, Ryschich, Eduard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226708/
https://www.ncbi.nlm.nih.gov/pubmed/25238265