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Selective methioninase-induced trap of cancer cells in S/G(2) phase visualized by FUCCI imaging confers chemosensitivity

A major impediment to the response of tumors to chemotherapy is that the large majority of cancer cells within a tumor are quiescent in G(0)/G(1), where cancer cells are resistant to chemotherapy. To attempt to solve this problem of quiescent cells in a tumor, cancer cells were treated with recombin...

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Detalles Bibliográficos
Autores principales: Yano, Shuya, Li, Shukuan, Han, Qinghong, Tan, Yuying, Bouvet, Michael, Fujiwara, Toshiyoshi, Hoffman, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226717/
https://www.ncbi.nlm.nih.gov/pubmed/25238266