Effects of PI3Kγ overexpression in the hippocampus on synaptic plasticity and spatial learning

Previous studies have shown that a family of phosphoinositide 3-kinases (PI3Ks) plays pivotal roles in the brain; in particular, we previously reported that knockout of the γ isoform of PI3K (PI3Kγ) in mice impaired synaptic plasticity and reduced behavioral flexibility. To further examine the role...

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Detalles Bibliográficos
Autores principales: Choi, Jun-Hyeok, Park, Pojeong, Baek, Gi-Chul, Sim, Su-Eon, Kang, SukJae Joshua, Lee, Yeseul, Ahn, Seo-Hee, Lim, Chae-Seok, Lee, Yong-Seok, Collingridge, Graham L, Kaang, Bong-Kiun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226891/
https://www.ncbi.nlm.nih.gov/pubmed/25373491
http://dx.doi.org/10.1186/s13041-014-0078-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226891/
https://www.ncbi.nlm.nih.gov/pubmed/25373491
http://dx.doi.org/10.1186/s13041-014-0078-6

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