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Experimental evaluation does not reveal a direct effect of microRNA from the callipyge locus on DLK1 expression

BACKGROUND: Polar overdominance at the ovine callipyge (CLPG) locus involves the post-transcriptional trans-inhibition of DLK1 in skeletal muscle of CLPG/CLPG sheep. The abundant maternally expressed microRNAs (miRNAs) mapping to the imprinted DLK1-GTL2 domain are prime candidate mediators of this t...

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Detalles Bibliográficos
Autores principales: Cheng, Huijun, Xu, Xuewen, Hadfield, Tracy, Cockett, Noelle, Charlier, Carole, Georges, Michel, Takeda, Haruko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226911/
https://www.ncbi.nlm.nih.gov/pubmed/25359221
http://dx.doi.org/10.1186/1471-2164-15-944