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Insulator function and topological domain border strength scale with architectural protein occupancy
BACKGROUND: Chromosome conformation capture studies suggest that eukaryotic genomes are organized into structures called topologically associating domains. The borders of these domains are highly enriched for architectural proteins with characterized roles in insulator function. However, a majority...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226948/ https://www.ncbi.nlm.nih.gov/pubmed/24981874 http://dx.doi.org/10.1186/gb-2014-15-5-r82 |