Insulator function and topological domain border strength scale with architectural protein occupancy

BACKGROUND: Chromosome conformation capture studies suggest that eukaryotic genomes are organized into structures called topologically associating domains. The borders of these domains are highly enriched for architectural proteins with characterized roles in insulator function. However, a majority...

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Detalles Bibliográficos
Autores principales: Van Bortle, Kevin, Nichols, Michael H, Li, Li, Ong, Chin-Tong, Takenaka, Naomi, Qin, Zhaohui S, Corces, Victor G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226948/
https://www.ncbi.nlm.nih.gov/pubmed/24981874
http://dx.doi.org/10.1186/gb-2014-15-5-r82

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