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Protective role of frizzled-related protein B on matrix metalloproteinase induction in mouse chondrocytes
INTRODUCTION: Our objective was to investigate whether a lack of frizzled-related protein B (FrzB), an extracellular antagonist of the Wnt signaling pathways, could enhance cartilage degradation by facilitating the expression, release and activation of matrix metalloproteinases (MMPs) by chondrocyte...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226985/ https://www.ncbi.nlm.nih.gov/pubmed/24984954 http://dx.doi.org/10.1186/ar4599 |