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A spatial simulation approach to account for protein structure when identifying non-random somatic mutations

BACKGROUND: Current research suggests that a small set of “driver” mutations are responsible for tumorigenesis while a larger body of “passenger” mutations occur in the tumor but do not progress the disease. Due to recent pharmacological successes in treating cancers caused by driver mutations, a va...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Ryslik, Gregory A, Cheng, Yuwei, Cheung, Kei-Hoi, Bjornson, Robert D, Zelterman, Daniel, Modis, Yorgo, Zhao, Hongyu
বিন্যাস: Online প্রবন্ধ পাঠ‍্য
ভাষা:English
প্রকাশিত: BioMed Central 2014
বিষয়গুলি:
অনলাইন ব্যবহার করুন:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227039/
https://www.ncbi.nlm.nih.gov/pubmed/24990767
http://dx.doi.org/10.1186/1471-2105-15-231