The glucuronyltransferase B4GAT1 is required for initiation of LARGE-mediated α-dystroglycan functional glycosylation

Dystroglycan is a cell membrane receptor that organizes the basement membrane by binding ligands in the extracellular matrix. Proper glycosylation of the α-dystroglycan (α-DG) subunit is essential for these activities, and lack thereof results in neuromuscular disease. Currently, neither the glycan...

Descripción completa

Detalles Bibliográficos
Autores principales: Willer, Tobias, Inamori, Kei-ichiro, Venzke, David, Harvey, Corinne, Morgensen, Greg, Hara, Yuji, Beltrán Valero de Bernabé, Daniel, Yu, Liping, Wright, Kevin M, Campbell, Kevin P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227050/
https://www.ncbi.nlm.nih.gov/pubmed/25279699
http://dx.doi.org/10.7554/eLife.03941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227050/
https://www.ncbi.nlm.nih.gov/pubmed/25279699
http://dx.doi.org/10.7554/eLife.03941

Ejemplares similares