Cargando…
The glucuronyltransferase B4GAT1 is required for initiation of LARGE-mediated α-dystroglycan functional glycosylation
Dystroglycan is a cell membrane receptor that organizes the basement membrane by binding ligands in the extracellular matrix. Proper glycosylation of the α-dystroglycan (α-DG) subunit is essential for these activities, and lack thereof results in neuromuscular disease. Currently, neither the glycan...
Autores principales: | Willer, Tobias, Inamori, Kei-ichiro, Venzke, David, Harvey, Corinne, Morgensen, Greg, Hara, Yuji, Beltrán Valero de Bernabé, Daniel, Yu, Liping, Wright, Kevin M, Campbell, Kevin P |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227050/ https://www.ncbi.nlm.nih.gov/pubmed/25279699 http://dx.doi.org/10.7554/eLife.03941 |
Ejemplares similares
-
Xylosyl- and glucuronyltransferase functions of LARGE in α-dystroglycan modification are conserved in LARGE2
por: Inamori, Kei-ichiro, et al.
Publicado: (2013) -
B4GAT1 is the priming enzyme for the LARGE-dependent functional glycosylation of α-dystroglycan
por: Praissman, Jeremy L, et al.
Publicado: (2014) -
N-terminal domain on dystroglycan enables LARGE1 to extend matriglycan on α-dystroglycan and prevents muscular dystrophy
por: Okuma, Hidehiko, et al.
Publicado: (2023) -
Loss of α-Dystroglycan Laminin Binding in Epithelium-derived
Cancers Is Caused by Silencing of
LARGE
por: de Bernabé, Daniel Beltrán-Valero, et al.
Publicado: (2009) -
Functional Glycosylation of Dystroglycan Is Crucial for Thymocyte Development in the Mouse
por: Liou, Li-Ying, et al.
Publicado: (2010)