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Suppression of the epithelial-mesenchymal transition by SHARP1 is linked to the NOTCH1 signaling pathway in metastasis of endometrial cancer

BACKGROUND: Mechanisms governing the metastasis of endometrial cancer (EC) are poorly defined. Recent data support a role for Enhancer-of-split and hairy-related protein 1 (SHARP1), a basic helix-loop-helix transcription repressor, in regulating invasiveness and angiogenesis of several human cancers...

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Detalles Bibliográficos
Autores principales: Liao, Yun, He, Xiaoying, Qiu, Haifeng, Che, Qi, Wang, Fangyuan, Lu, Wen, Chen, Zheng, Qiu, Meiting, Wang, Jingyun, Wang, Huihui, Wan, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227067/
https://www.ncbi.nlm.nih.gov/pubmed/24997474
http://dx.doi.org/10.1186/1471-2407-14-487