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Baicalein, an active component of Scutellaria baicalensis Georgi, prevents lysophosphatidylcholine-induced cardiac injury by reducing reactive oxygen species production, calcium overload and apoptosis via MAPK pathways

BACKGROUND: Lysophosphatidylcholine (lysoPC), a metabolite from membrane phospholipids, accumulates in the ischemic myocardium and plays an important role in the development of myocardial dysfunction ventricular arrhythmia. In this study, we investigated if baicalein, a major component of Huang Qui,...

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Detalles Bibliográficos
Autores principales: Chen, Huai-Min, Hsu, Jong-Hau, Liou, Shu-Fen, Chen, Tsan-Ju, Chen, Li-Ying, Chiu, Chaw-Chi, Yeh, Jwu-Lai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227070/
https://www.ncbi.nlm.nih.gov/pubmed/25012390
http://dx.doi.org/10.1186/1472-6882-14-233