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Combinatorial Measurement of CDKN1A/p21 and KIF20A Expression for Discrimination of DNA Damage-Induced Clastogenicity

In vitro mammalian cytogenetic tests detect chromosomal aberrations and are used for testing the genotoxicity of compounds. This study aimed to identify a supportive genomic biomarker could minimize the risk of misjudgments and aid appropriate decision making in genotoxicity testing. Human lymphobla...

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Detalles Bibliográficos
Autores principales: Sakai, Rina, Morikawa, Yuji, Kondo, Chiaki, Oka, Hiroyuki, Miyajima, Hirofumi, Kubo, Kihei, Uehara, Takeki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227160/
https://www.ncbi.nlm.nih.gov/pubmed/25264741
http://dx.doi.org/10.3390/ijms151017256