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Effect of APE1 T2197G (Asp148Glu) Polymorphism on APE1, XRCC1, PARP1 and OGG1 Expression in Patients with Colorectal Cancer

It has been hypothesized that genetic variation in base excision repair (BER) might modify colorectal adenoma risk. Thus, we evaluated the influence of APE1 T2197G (Asp148Glu) polymorphism on APE1, XRCC1, PARP1 and OGG1 expression in normal and tumor samples from patients with colorectal cancer. The...

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Detalles Bibliográficos
Autores principales: Santos, Juliana C., Funck, Alexandre, Silva-Fernandes, Isabelle J. L., Rabenhorst, Silvia H. B., Martinez, Carlos A. R., Ribeiro, Marcelo L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227165/
https://www.ncbi.nlm.nih.gov/pubmed/25268610
http://dx.doi.org/10.3390/ijms151017333