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The Biological Function and Clinical Utilization of CD147 in Human Diseases: A Review of the Current Scientific Literature
CD147 or EMMPRIN is a member of the immunoglobulin superfamily in humans. It is widely expressed in human tumors and plays a central role in the progression of many cancers by stimulating the secretion of matrix metalloproteinases (MMPs) and cytokines. CD147 regulates cell proliferation, apoptosis,...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227170/ https://www.ncbi.nlm.nih.gov/pubmed/25268615 http://dx.doi.org/10.3390/ijms151017411 |