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TCDD Induces the Hypoxia-Inducible Factor (HIF)-1α Regulatory Pathway in Human Trophoblastic JAR Cells

The exposure to dioxin can compromise pregnancy outcomes and increase the risk of preterm births. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) has been demonstrated to induce placental hypoxia at the end of pregnancy in a rat model, and hypoxia has been suggested to be the cause of abnormal trophoblas...

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Detalles Bibliográficos
Autores principales: Liao, Tien-Ling, Chen, Su-Chee, Tzeng, Chii-Reuy, Kao, Shu-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227186/
https://www.ncbi.nlm.nih.gov/pubmed/25272228
http://dx.doi.org/10.3390/ijms151017733