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FOXO1 Content Is Reduced in Cystic Fibrosis and Increases with IGF-I Treatment

Cystic fibrosis-related diabetes is to date the most frequent complication in cystic fibrosis (CF). The mechanisms underlying this condition are not well understood, and a possible role of insulin resistance is debated. We investigated insulin signal transduction in CF. Total insulin receptor, IRS1,...

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Detalles Bibliográficos
Autores principales: Smerieri, Arianna, Montanini, Luisa, Maiuri, Luigi, Bernasconi, Sergio, Street, Maria E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227201/
https://www.ncbi.nlm.nih.gov/pubmed/25299696
http://dx.doi.org/10.3390/ijms151018000