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Preparation and Evaluation of Human-Murine Chimeric Antibody against Protective Antigen of Bacillus anthracis
The aim of this research is to develop a human/murine chimeric Fab antibody which neutralizes the anthrax toxin, protective antigen (PA). The chimeric Fab was constructed using variable regions of murine anti-PA monoclonal antibody in combination with constant regions of human IgG. The chimeric PA6-...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227228/ https://www.ncbi.nlm.nih.gov/pubmed/25318053 http://dx.doi.org/10.3390/ijms151018496 |