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Preparation and Evaluation of Human-Murine Chimeric Antibody against Protective Antigen of Bacillus anthracis

The aim of this research is to develop a human/murine chimeric Fab antibody which neutralizes the anthrax toxin, protective antigen (PA). The chimeric Fab was constructed using variable regions of murine anti-PA monoclonal antibody in combination with constant regions of human IgG. The chimeric PA6-...

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Detalles Bibliográficos
Autores principales: Hao, Lina, Zheng, Feng, Xiong, Siping, Hu, Dan, Lv, Heng, Tang, Qi, Yang, Jin, Feng, Zhenqing, Wang, Changjun, Zhu, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227228/
https://www.ncbi.nlm.nih.gov/pubmed/25318053
http://dx.doi.org/10.3390/ijms151018496