Cargando…
Preparation and Evaluation of Human-Murine Chimeric Antibody against Protective Antigen of Bacillus anthracis
The aim of this research is to develop a human/murine chimeric Fab antibody which neutralizes the anthrax toxin, protective antigen (PA). The chimeric Fab was constructed using variable regions of murine anti-PA monoclonal antibody in combination with constant regions of human IgG. The chimeric PA6-...
Autores principales: | Hao, Lina, Zheng, Feng, Xiong, Siping, Hu, Dan, Lv, Heng, Tang, Qi, Yang, Jin, Feng, Zhenqing, Wang, Changjun, Zhu, Jin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227228/ https://www.ncbi.nlm.nih.gov/pubmed/25318053 http://dx.doi.org/10.3390/ijms151018496 |
Ejemplares similares
-
A Novel Chimeric Anti-PA Neutralizing Antibody for Postexposure Prophylaxis and Treatment of Anthrax
por: Xiong, Siping, et al.
Publicado: (2015) -
Human monoclonal anti-protective antigen antibody for the low-dose post-exposure prophylaxis and treatment of Anthrax
por: Tang, Qi, et al.
Publicado: (2018) -
Isolation and Chimerization of a Highly Neutralizing Antibody Conferring Passive Protection against Lethal Bacillus anthracis Infection
por: Rosenfeld, Ronit, et al.
Publicado: (2009) -
Molecularly Targeted Therapy of Human Hepatocellular Carcinoma Xenografts with Radio-iodinated Anti-VEGFR2 Murine-Human Chimeric Fab
por: Huang, Jianfei, et al.
Publicado: (2015) -
Activity of the Bacillus anthracis 20 kDa protective antigen component
por: Hammamieh, Rasha, et al.
Publicado: (2008)