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Association between the Hypomethylation of Osteopontin and Integrin β3 Promoters and Vascular Smooth Muscle Cell Phenotype Switching in Great Saphenous Varicose Veins

Lower extremity varicose veins are a common condition in vascular surgery and proliferation of vascular smooth muscle cells (VSMCs) in the intima is a significant pathological feature of varicosity. However, the pathogenesis of varicose veins is not fully understood. Osteopontin (OPN) could promote...

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Detalles Bibliográficos
Autores principales: Jiang, Han, Lun, Yu, Wu, Xiaoyu, Xia, Qian, Zhang, Xiaoyu, Xin, Shijie, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227244/
https://www.ncbi.nlm.nih.gov/pubmed/25329616
http://dx.doi.org/10.3390/ijms151018747