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Khz-cp (crude polysaccharide extract obtained from the fusion of Ganoderma lucidum and Polyporus umbellatus mycelia) induces apoptosis by increasing intracellular calcium levels and activating P38 and NADPH oxidase-dependent generation of reactive oxygen species in SNU-1 cells

BACKGROUND: Khz-cp is a crude polysaccharide extract that is obtained after nuclear fusion in Ganoderma lucidum and Polyporus umbellatus mycelia (Khz). It inhibits the growth of cancer cells. METHODS: Khz-cp was extracted by solvent extraction. The anti-proliferative activity of Khz-cp was confirmed...

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Detalles Bibliográficos
Autores principales: Kim, Tae Hwan, Kim, Ju Sung, Kim, Zoo Haye, Huang, Ren Bin, Chae, Young Lye, Wang, Ren Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227278/
https://www.ncbi.nlm.nih.gov/pubmed/25012725
http://dx.doi.org/10.1186/1472-6882-14-236