Chromosome-breakage genomic instability and chromothripsis in breast cancer

BACKGROUND: Chromosomal breakage followed by faulty DNA repair leads to gene amplifications and deletions in cancers. However, the mere assessment of the extent of genomic changes, amplifications and deletions may reduce the complexity of genomic data observed by array comparative genomic hybridizat...

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Detalles Bibliográficos
Autores principales: Przybytkowski, Ewa, Lenkiewicz, Elizabeth, Barrett, Michael T, Klein, Kathleen, Nabavi, Sheida, Greenwood, Celia MT, Basik, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227294/
https://www.ncbi.nlm.nih.gov/pubmed/25011954
http://dx.doi.org/10.1186/1471-2164-15-579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227294/
https://www.ncbi.nlm.nih.gov/pubmed/25011954
http://dx.doi.org/10.1186/1471-2164-15-579

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