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A cross-sectional study of global DNA methylation and risk of colorectal adenoma

BACKGROUND: The methylation of DNA is recognized as a key epigenetic mechanism and evidence for its role in the development of several malignancies is accumulating. We evaluated the relationship between global methylation in DNA derived from normal appearing colon mucosal tissue and blood leukocytes...

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Detalles Bibliográficos
Autores principales: King, Will D, Ashbury, Janet E, Taylor, Sherryl A, Tse, M Yat, Pang, Stephen C, Louw, Jacob A, Vanner, Stephen J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227295/
https://www.ncbi.nlm.nih.gov/pubmed/24998982
http://dx.doi.org/10.1186/1471-2407-14-488