Sample size requirements to estimate key design parameters from external pilot randomised controlled trials: a simulation study

BACKGROUND: External pilot or feasibility studies can be used to estimate key unknown parameters to inform the design of the definitive randomised controlled trial (RCT). However, there is little consensus on how large pilot studies need to be, and some suggest inflating estimates to adjust for the...

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Detalles Bibliográficos
Autores principales: Teare, M Dawn, Dimairo, Munyaradzi, Shephard, Neil, Hayman, Alex, Whitehead, Amy, Walters, Stephen J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227298/
https://www.ncbi.nlm.nih.gov/pubmed/24993581
http://dx.doi.org/10.1186/1745-6215-15-264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227298/
https://www.ncbi.nlm.nih.gov/pubmed/24993581
http://dx.doi.org/10.1186/1745-6215-15-264

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