Large-Scale Label-Free Comparative Proteomics Analysis of Polo-Like Kinase 1 Inhibition via the Small-Molecule Inhibitor BI 6727 (Volasertib) in BRAF(V600E) Mutant Melanoma Cells

[Image: see text] Polo-like kinase 1 (Plk1) is a serine/threonine kinase that plays a key role during the cell cycle by regulating mitotic entry, progression, and exit. Plk1 is overexpressed in a variety of human cancers and is essential to sustained oncogenic proliferation, thus making Plk1 an attr...

Descripción completa

Detalles Bibliográficos
Autores principales: Cholewa, Brian D., Pellitteri-Hahn, Molly C., Scarlett, Cameron O., Ahmad, Nihal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227549/
https://www.ncbi.nlm.nih.gov/pubmed/24884503
http://dx.doi.org/10.1021/pr5002516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227549/
https://www.ncbi.nlm.nih.gov/pubmed/24884503
http://dx.doi.org/10.1021/pr5002516

Ejemplares similares