Integrated Approaches for Analyzing U1-70K Cleavage in Alzheimer’s Disease

[Image: see text] The accumulation of pathologic protein fragments is common in neurodegenerative disorders. We have recently identified in Alzheimer’s disease (AD) the aggregation of the U1-70K splicing factor and abnormal RNA processing. Here, we present that U1-70K can be cleaved into an N-termin...

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Detalles Bibliográficos
Autores principales: Bai, Bing, Chen, Ping-Chung, Hales, Chadwick M., Wu, Zhiping, Pagala, Vishwajeeth, High, Anthony A., Levey, Allan I., Lah, James J., Peng, Junmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227550/
https://www.ncbi.nlm.nih.gov/pubmed/24902715
http://dx.doi.org/10.1021/pr5003593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227550/
https://www.ncbi.nlm.nih.gov/pubmed/24902715
http://dx.doi.org/10.1021/pr5003593

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